Strasbourg dominated the match, with goals from Martial Godo and Diego Moreira giving them a 2-0 lead before halftime. Corentin Tolisso pulled one back for Lyon, but Joaquin Panichelli restored the two-goal cushion from the penalty spot.
This result allows Strasbourg to climb to seventh place in the table, while Lyon missed the chance to extend their lead over Marseille and remains in a precarious position.