The Viola won 3-0 at Bialystok, with Luca Ranieri, Rolando Mandragora and Roberto Piccoli finding the net. The victory guarantees Fiorentina a spot in the Conference League last 16.
The side travelled without injured David De Gea, Moise Kean, Dodo, Manor Solomon and Albert Gudmundsson, and cup‑tied Marco Brescianini, Oliver Christensen and Daniele Rugani. Luca Lezzerini made his second UEFA appearance after a 2016 defeat to PAOK.